Sintongchugoetang(CTCOT) is one of the importent prescription that has been used in oriental medicine(yyilimgaechak) for helling fractured condition. The study was done to evaluate effects of CTCOTwater extract on the tibia fractured rats.
The result were obtained as follows :
1. In the change of X-ray, experimental group was significantly effected than control.
2. In the changes of body weight, experimental group was decreased than control.
3. In the change of Ca, P and ALP(alkaline phosphatase) on serum, all experimental group was not significant.
4. In the change of bone tissue, experimental group was was significantly effected than control in callus formation and maturity.
From above results, CTCOT was had significant effects on the helling of fractured in rats, so it is expected to clinical application.
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